{"title":"粘膜内施万细胞性过误瘤(mucosal Schwann cell hamartoma)的一个例子","authors":"Shintaro Sagami, Akira Fukumoto, Mio Amano, Kentaro Yamao, Yoshimasa Hashimoto, Tomohiro Iiboshi, Seiji Onogawa, Naomichi Hirano, Keiji Hanada, Hajime Amano, Fumiaki Hino, S. Yonehara","doi":"10.11405/NISSHOSHI.109.1776","DOIUrl":null,"url":null,"abstract":": A 40-year-old man was referred to our hospital because of a positive fecal occult blood test. Colonoscopy revealed many small whitish nodules in the mucosa of the sigmoid colon. Specimens endoscopically resected from the lesions revealed spindle cell proliferation in the lamina propria. Immunohistochemical study revealed strong and diffuse positivity for S-100 protein. Results of staining for neurofilament protein and epithelial membrane antigen were negative. The neurogenic tumors were diagnosed as mucosal Schwann cell hamartoma. No clinical features of multiple endocrine neoplasia type 2B or neurofibromatosis type 1 were found in the present case.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"54 46 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2012-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"粘膜内シュワン細胞性過誤腫 (mucosal Schwann cell hamartoma) の1例\",\"authors\":\"Shintaro Sagami, Akira Fukumoto, Mio Amano, Kentaro Yamao, Yoshimasa Hashimoto, Tomohiro Iiboshi, Seiji Onogawa, Naomichi Hirano, Keiji Hanada, Hajime Amano, Fumiaki Hino, S. Yonehara\",\"doi\":\"10.11405/NISSHOSHI.109.1776\",\"DOIUrl\":null,\"url\":null,\"abstract\":\": A 40-year-old man was referred to our hospital because of a positive fecal occult blood test. Colonoscopy revealed many small whitish nodules in the mucosa of the sigmoid colon. Specimens endoscopically resected from the lesions revealed spindle cell proliferation in the lamina propria. Immunohistochemical study revealed strong and diffuse positivity for S-100 protein. Results of staining for neurofilament protein and epithelial membrane antigen were negative. The neurogenic tumors were diagnosed as mucosal Schwann cell hamartoma. No clinical features of multiple endocrine neoplasia type 2B or neurofibromatosis type 1 were found in the present case.\",\"PeriodicalId\":341053,\"journal\":{\"name\":\"The Japanese journal of gastro-enterology\",\"volume\":\"54 46 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-10-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Japanese journal of gastro-enterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.11405/NISSHOSHI.109.1776\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Japanese journal of gastro-enterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11405/NISSHOSHI.109.1776","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
: A 40-year-old man was referred to our hospital because of a positive fecal occult blood test. Colonoscopy revealed many small whitish nodules in the mucosa of the sigmoid colon. Specimens endoscopically resected from the lesions revealed spindle cell proliferation in the lamina propria. Immunohistochemical study revealed strong and diffuse positivity for S-100 protein. Results of staining for neurofilament protein and epithelial membrane antigen were negative. The neurogenic tumors were diagnosed as mucosal Schwann cell hamartoma. No clinical features of multiple endocrine neoplasia type 2B or neurofibromatosis type 1 were found in the present case.
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