{"title":"阿尔茨海默病的基因治疗、细胞治疗和基于细胞的基因治疗综述","authors":"A. Chakraborty, Anil Diwan","doi":"10.33582/mpnns.2022.202203001","DOIUrl":null,"url":null,"abstract":"Alzheimer’s disease (AD) is known as an age-related neurodegenerative disease where progressive loss of memory associated with cognition defects has been noticed. Molecular analysis of AD revealed the formation of aggregated amyloid-β protein and hyper phosphorylated tau tangles at the synaptic circuit, which causes the loss of neuronal communication.","PeriodicalId":305865,"journal":{"name":"MedPress Neurology and Neurosurgery","volume":"23 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Brief Notes on Gene Therapy, Cell Therapy and Cell-Based Gene Therapy for Alzheimer’s Disease\",\"authors\":\"A. Chakraborty, Anil Diwan\",\"doi\":\"10.33582/mpnns.2022.202203001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Alzheimer’s disease (AD) is known as an age-related neurodegenerative disease where progressive loss of memory associated with cognition defects has been noticed. Molecular analysis of AD revealed the formation of aggregated amyloid-β protein and hyper phosphorylated tau tangles at the synaptic circuit, which causes the loss of neuronal communication.\",\"PeriodicalId\":305865,\"journal\":{\"name\":\"MedPress Neurology and Neurosurgery\",\"volume\":\"23 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-03-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"MedPress Neurology and Neurosurgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33582/mpnns.2022.202203001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"MedPress Neurology and Neurosurgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33582/mpnns.2022.202203001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Brief Notes on Gene Therapy, Cell Therapy and Cell-Based Gene Therapy for Alzheimer’s Disease
Alzheimer’s disease (AD) is known as an age-related neurodegenerative disease where progressive loss of memory associated with cognition defects has been noticed. Molecular analysis of AD revealed the formation of aggregated amyloid-β protein and hyper phosphorylated tau tangles at the synaptic circuit, which causes the loss of neuronal communication.
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