S Balabanova, E Schneider, R Wepler, B Hermann, H J Boschek, H Scheitler
{"title":"匹罗卡品汗液药物测定对既往用药的检测意义。","authors":"S Balabanova, E Schneider, R Wepler, B Hermann, H J Boschek, H Scheitler","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The presence of cocaine, morphine and methadone in sweat samples obtained after stimulation of the eccrine sweat glands, from drugs users after six drugs-free days, was investigated. The stimulation of the sweat elimination was proved using pilocarpine-iontophoresis every hour for 7 hours. The drugs concentrations were determined by radioimmunoassay. Consequently, the values measured represent the sum of the drug and its metabolites. Measurable levels of cocaine, morphine and methadone were obtained after the third stimulation of the glands.</p>","PeriodicalId":75580,"journal":{"name":"Beitrage zur gerichtlichen Medizin","volume":"50 ","pages":"111-5"},"PeriodicalIF":0.0000,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Significance of drug determination in pilocarpine sweat for detection of past drug abuse].\",\"authors\":\"S Balabanova, E Schneider, R Wepler, B Hermann, H J Boschek, H Scheitler\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The presence of cocaine, morphine and methadone in sweat samples obtained after stimulation of the eccrine sweat glands, from drugs users after six drugs-free days, was investigated. The stimulation of the sweat elimination was proved using pilocarpine-iontophoresis every hour for 7 hours. The drugs concentrations were determined by radioimmunoassay. Consequently, the values measured represent the sum of the drug and its metabolites. Measurable levels of cocaine, morphine and methadone were obtained after the third stimulation of the glands.</p>\",\"PeriodicalId\":75580,\"journal\":{\"name\":\"Beitrage zur gerichtlichen Medizin\",\"volume\":\"50 \",\"pages\":\"111-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1992-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Beitrage zur gerichtlichen Medizin\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Beitrage zur gerichtlichen Medizin","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Significance of drug determination in pilocarpine sweat for detection of past drug abuse].
The presence of cocaine, morphine and methadone in sweat samples obtained after stimulation of the eccrine sweat glands, from drugs users after six drugs-free days, was investigated. The stimulation of the sweat elimination was proved using pilocarpine-iontophoresis every hour for 7 hours. The drugs concentrations were determined by radioimmunoassay. Consequently, the values measured represent the sum of the drug and its metabolites. Measurable levels of cocaine, morphine and methadone were obtained after the third stimulation of the glands.
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