丹金草对血管紧张素转换酶I的抑制活性

2021 5th International Symposium on Multidisciplinary Studies and Innovative Technologies (ISMSIT) Pub Date : 2021-10-21 DOI:10.1109/ISMSIT52890.2021.9604664

A. Zeytunluoglu, I. Arslan

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引用次数: 0

摘要

本研究旨在评价土耳其天然产金缕草对血管紧张素转换酶I (ACE-I)的抑制活性、抗氧化能力和酚类物质。本文采用羊羊膜水提液对羊肺中纯化的血管紧张素转换酶I进行酶抑制实验。此外，还采用Trolox等效抗氧化能力(TEAC)和DPPH测定法监测甲醇和水溶液提取物的抗氧化特性。并对其总酚类物质进行了分析。我们的研究结果表明，枸杞对血管紧张素转换酶I的抑制作用可能具有重要的抗高血压作用。

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Inhibitory Activity Towards Angiotensin Converting Enzyme I of Alchemilla vulgaris

The study was aimed to evaluate the inhibitory activity towards angiotensin converting enzyme I (ACE-I), antioxidant capacity and phenolics of Alchemilla vulgaris (lady’s mantle) naturally grows in Turkey. Aqueous extracts of lady’s mantle were used for enzyme inhibition assay on angiotensin converting enzyme I purified from sheep lungs. Trolox equivalent antioxidant capacity (TEAC) and DPPH assays were also used for monitoring of antioxidant profile of methanolic and aqueous extracts. Total phenolics of the extracts from lady’s mantle were also analyzed. Our research results indicated that lady’s mantle could have important anti-hypertensive effects due to their potent inhibitory activity towards angiotensin converting enzyme I.

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2021 5th International Symposium on Multidisciplinary Studies and Innovative Technologies (ISMSIT)

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