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Indonesian Journal of Obstetrics & Gynecology Science Pub Date : 2019-03-29 DOI:10.24198/OBGYNIA.V2N1.65

Aria Prasetya Masoem, Tono Djuwantono, M. A. Ritonga, J. Effendi, Wiryawan Permadi, Tita Husnitawati Madjid

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引用次数: 1

摘要

摘要目的:本研究旨在比较尿道外和非尿道外血清中25-羟基-维生素D3的差异。方法:本研究是一项具有对联交叉设计的分析研究。研究对象是生殖年龄的妇女，她们接受了符合研究纳入标准的拉皮切除术/腹腔镜检查(n=42)。研究对象分为两组，即uteri miom组(n=21)和非uteri类(n=21)。两组进行血清25-维生素D3检测，然后进行电化学发光(ECLIA)。这个研究万隆RSUP哈桑Sadikin博士在2017年8月−6月。结果:研究表明，子宫内的平均D3次维生素d - 3浓度为6.70 (3.29)ng/ml，而非子宫色素瘤群体为10.34 (2.79)ng/ml。这两组中25-羟基-维生素D3的平均水平分别为p . < 001。然而，25-水文D3与中微子质量之间的相关性并不存在。结论:子宫内麻黄素组中的25-营养素D3含量低于非子宫微生物组。关键词:子宫外肌、维生素D、25-维生素D3 Abstract对象:这项研究的目标是确定25-水-维生素D3中uterine fibroid group和非uterine fibroid group之间的影响是否有明显的差异。方法:这是一种观察分析研究，具有跨界综合方法。研究对象是在失业后进行腹腔镜/腹腔镜检查的妇女(n=42)。研究对象被分为两个groups, uterine fibroid group (n=21)和非uterine fibroid (n=21)。血清25-氢-维生素D3的测量是通过电化学发光(ECLIA)方法进行检测。at The study was conducted哈桑博士在琼−Sadikin医院2017年八月。再生:再生组织在uterine肌broid小组中呈现出平均水平为6.70 (3.29)ng/ml和非uterine纤维化小组10.34 (2.79)ng/ml。在uterine纤维组和非uterine纤维组，p值小于0.001的血清之间存在显著的不同。但是，在一种血清中没有相关性。结论:血清的水平是25-羟基维生素D3的uterine纤维化小组，而不是非uterine纤维化小组。关键词:Uterine fibroid，维生素D, 25-羟基维生素D3

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Perbandingan Kadar 25-(OH)-Vitamin D3 pada Serum Kelompok Mioma Uteri dan Non-Mioma Uteri

Abstrak Tujuan : Penelitian ini bertujuan untuk membandingkan perbedaan kadar 25-hidroksi-vitamin D3 pada serum kelompok mioma uteri dan non-mioma uteri. Metode : Penelitian ini merupakan penelitian analitik observasional dengan rancangan komparatif cross sectional. Subjek penelitian adalah wanita usia reproduksi yang menjalani prosedur laparatomi/laparaskopi yang memenuhi kriteria inklusi penelitian (n=42). Subjek penelitian dibagi menjadi dua kelompok, yakni kelompok mioma uteri (n=21) dan non-mioma uteri (n=21). Pada kedua kelompok dilakukan pemeriksaan kadar serum 25-hidroksi-vitamin D3 kemudian diperiksa dengan metode Electro-chemiluminescence Immunoassay (ECLIA). Penelitian ini dilakukan di RSUP Dr. Hasan Sadikin Bandung pada bulan Juni−Agustus 2017. Hasil : Hasil penelitian menunjukkan kadar 25-hidroksi-vitamin D3 rata-rata pada kelompok mioma uteri adalah 6,70 (3,29) ng/ml, sementara pada kelompok non-mioma uteri 10,34 (2,79) ng/ml. Perbedaan kadar rata-rata 25-hidroksi-vitamin D3 pada kedua kelompok tersebut bermakna dengan nilai p<0,001. Namun, tidak didapatkan korelasi antara kadar 25-hidroksi-vitamin D3 dengan berat massa mioma uteri. Kesimpulan : Kadar 25-hidroksi-vitamin D3 pada kelompok mioma uteri lebih rendah dibandingkan dengan kelompok non-mioma uteri. Key words : Mioma uteri, vitamin D, 25-hidroksi-vitamin D3 Abstract Objective : The aim of this study was to determine if there is any significant difference between serum levels of 25-hydroxy-vitamin D3 of uterine fibroid group and non-uterine fibroid group. Method : This was an observational analytic study with comparative cross-sectional method. Subjects were women in reproductive age who underwent laparotomy / laparoscopy procedures who met the study criteria (n=42). The subjects were divided into two groups, uterine fibroid group (n=21) and non-uterine fibroid (n=21). Measurement of serum 25-hydroxy-vitamin D3 was performed using Electro-chemiluminescence Immunoassay (ECLIA) method. The study was conducted at Dr. Hasan Sadikin hospital in June−August 2017. Result : The results showed the mean level 25-hydroxy-vitamin D3 on uterine fibroid group was 6.70 (3.29) ng / ml and non-uterine fibroid group 10.34 (2.79) ng/ml. There was significant difference between serum level of 25-hydroxy-vitamin D3 in uterine fibroid group and non-uterine fibroid with p value <0.001. But, there was no correlation between serum level of 25-hydroxy-vitamin D3 content and the weight of uterine fibroid mass. Conclusions : Serum level of 25-hydroxy-vitamin D3 is lower in uterine fibroid group than non-uterine fibroid group. Key words : Uterine fibroid, vitamin D, 25-hydroxy-vitamin D3

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Indonesian Journal of Obstetrics & Gynecology Science

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