用室室模型模拟帕金森患者18F-FDOPA浓度变化

2020 17th International Conference on Electrical Engineering/Electronics, Computer, Telecommunications and Information Technology (ECTI-CON) Pub Date : 2020-06-01 DOI:10.1109/ecti-con49241.2020.9158267

Printaporn Sanguansuttigul, T. Saleewong, Kitiwat Khamwam, S. Bongsebandhu-Phubhakdi

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引用次数: 0

摘要

纹状体放射性物质18F-FDOPA浓度变化的研究是诊断帕金森病的重要技术之一。在研究中，我们采用室室模型研究18F-FDOPA通过大脑在纹状体区域的面积比例，并考虑在给定时间t下不同的浓度水平。我们特别采用室室动力学模型研究18F-FDOPA注射后随时间的行为。我们还计算了建模误差，并对我们的结果进行了后续讨论。

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Modelling the Concentration Changes of 18F-FDOPA using Compartmental Model in Parkinson Patients

The study on the concentration changes of the radioactive substance 18F-FDOPA in striatum is one of the important technique to diagnose the Parkinson’s disease (PD). In research, the compartment model is applied to study the area proportions of 18F-FDOPA through the brain in the striatum area and consider different concentration levels at a given time t. In particular, we adopt compartmental dynamic model to study the behaviour of 18F-FDOPA over times after the injection. We also compute the modelling errors and give subsequent discussion about our results.

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2020 17th International Conference on Electrical Engineering/Electronics, Computer, Telecommunications and Information Technology (ECTI-CON)

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