基于微阵列基因表达数据的癌症类型分类的简化CAD系统

Sawssen Bacha, O. Taouali, N. Liouane
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引用次数: 0

摘要

癌症是危害人类健康的最致命疾病之一。癌症的分类给生物医学研究带来了许多挑战,因为它允许准确有效的诊断,并保证医学治疗的成功。本文在MATLAB (version R2016a)环境下实现了一种新的简化计算机辅助诊断(CAD)系统,对四种癌症亚型进行分类。实验结果是用四组癌症基因表达的基线数据进行的。为了验证所提出的CAD系统,测量了不同的性能指标,如灵敏度、特异性、准确性和F-Score。实验分析证明了所提出模型的有效性,因此,该模型可以被认为是帮助放射科医生更好地诊断的有效工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Reduced CAD system for classifications of cancer types based on microarray gene expression data
Cancer is one of the deadliest diseases for human health. The classification of cancers poses many challenges in biomedical research because it allows an accurate and effective diagnosis and guarantees the success of medical treatments. In this paper, a new reduced Computer-Aided Diagnosis (CAD) system is implemented under the MATLAB (version R2016a) environment to classifying four cancer subtypes. The results of the experiment are carried out with four sets of baseline data on the expression of cancer genes. To validate the proposed CAD system, different performance metrics such as sensitivity, specificity, accuracy, and F-Score are measured. The experimental analysis justifies the effectiveness of the proposed model and, therefore, this model can be considered as an effective tool to help radiologists for a better diagnosis.
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