糖尿病患者结膜菌群

N. Nahar, S. Anwar, R. Miah
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引用次数: 5

摘要

结膜菌群是指居住在健康人眼睛内的微生物种群,对维持健康的眼表和正常的结膜功能很重要。结膜菌群可能受到多种因素的影响,包括年龄、免疫抑制和地理位置。糖尿病患者的免疫功能受损。本研究的目的是观察糖尿病和非糖尿病患者结膜细菌菌群的模式。本横断面研究于2011年1月至2011年12月在BSMMU进行。收集50例就诊于BSMMU内分泌科门诊的糖尿病患者和200例非糖尿病患者的双眼结膜拭子共500份。糖尿病患者(64.0%)的培养阳性显著高于非糖尿病患者(38.0%)。表皮葡萄球菌在两个研究组中均占主导地位(糖尿病vs非糖尿病:41.3% vs 65.26%)。糖尿病患者中检出金黄色葡萄球菌(15.22%)、大肠杆菌(6.52%)和肠杆菌(8.33%)。糖尿病患者双眼和单眼培养阳性率(28%,36.0%)高于非糖尿病患者(9.5%,28.5%)。DOI: http://dx.doi.org/10.3329/imcj.v7i1.17698 Ibrahim Med. col。j . 2013;7 (1): 5 - 8
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Conjunctival bacterial flora in diabetic patients
Conjunctival flora refers to population of microorganisms that dwell within the eyes of healthy individuals and is important in maintaining a healthy ocular surface and normal conjunctival function. Conjunctival flora may be altered by a variety of factors that include age, immunosuppression and geography. Immune function is compromised in diabetes mellitus. The aim of the present study was to see the pattern of conjunctival bacterial flora in diabetic and non-diabetic patients. This cross sectional study was carried out in BSMMU during the period of January 2011 to December 2011. Total 500 conjunctival swabs were collected from both eyes of 50 diabetic patients attending OPD of Endocrinology Department of BSMMU and 200 non-diabetic individuals. Significant number of culture was positive in diabetic patients (64.0%) compared to that of non-diabetic individuals (38.0%). Staphylococcus epidermidis was predominant in both study groups (diabetic vs non-diabetic: 41.3% vs 65.26%). Staphylococcus aureus (15.22%), Escherichia coli (6.52%) and Enterobacter (8.33%) were isolated in diabetic patients. Rate of positive culture in both and single eyes were higher in diabetic (28%, 36.0%) than that of non-diabetic individuals (9.5%, 28.5%). DOI: http://dx.doi.org/10.3329/imcj.v7i1.17698 Ibrahim Med. Coll. J. 2013; 7(1): 5-8
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