雅加达住院老年患者使用Beers和STOPP标准进行潜在不适当药物识别的比较

D. Viviandhari, N. Nurhasnah, R. N. Sakinah, Desi Wulandari
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引用次数: 0

摘要

药物不良事件(ADE)与老年人潜在不适当用药(PIMs)密切相关,可导致发病率、死亡率和医疗费用的增加。通常用于评估pim的工具包括Beers和老年人处方筛选工具(STOPP)标准。因此,本研究旨在比较使用Beers 2019和STOPP 2016版2标准的pim识别。采用描述性分析方法,回顾性收集2018年Pondok Kopi伊斯兰医院340例患者的病历数据。结果显示,在符合Beers 2019纳入标准的324例患者中,有136例(41.85%)存在pim,共181例。符合标准3者最多,分别为速尿46例(25.41%)和螺内酯33例(18.23%)。同时,308例符合STOPP纳入标准的患者中,有14例(4.55%)出现pim,共18例。未控制的重度高血压患者中有7例(38.89%)使用阿司匹林或氯吡格雷,未控制的重度高血压患者中有3例(16.67%)使用非甾体抗炎药。同时使用醛固酮拮抗剂或ARB,并与其他升高钾的药物合用,未及时监测血钾水平的病例有3例(16.67%)。在Pondok Kopi伊斯兰医院,由于数据可用性,Beers 2019标准可以比STOPP 2016版本2更好地描述pim数据。临床医生和药剂师的合作也需要制定关键的支持数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Comparison of Potentially Inappropriate Medications Identification Using Beers and STOPP Criteria in Hospitalized Geriatric Patients in Jakarta
Adverse Drug Events (ADE) are closely related to Potentially Inappropriate Medications (PIMs) among the elderly, and can cause an increase in morbidity, mortality, and medical cost. The tools often used to assess PIMs include Beers and Screening Tool of Older Persons’ Prescriptions (STOPP) Criteria. Therefore, this study aimed to compare the PIMs identification using Beers 2019 and STOPP version 2 2016 Criteria. A descriptive-analytical method was used, and data were collected retrospectively from the medical records of 340 patients at Pondok Kopi Islamic Hospital period in 2018. The results showed that among 324 patients who met the inclusion criteria with Beers 2019, PIMs were present in 136 (41.85%), with 181 cases. Most of them were on criteria 3, namely 46 (25.41%) and 33 (18.23%) cases of furosemide and spironolactone, respectively. Meanwhile, out of 308 patients who met the inclusion criteria with STOPP, PIMs were found in 14 (4.55%) with a total of 18 cases. The use of aspirin or clopidogrel was observed in 7 people (38.89%) with uncontrolled severe hypertension, while NSAID usage was found in 3 uncontrolled severe hypertension patients (16.67%). Furthermore, there were 3 cases of aldosterone antagonist or ARB usage, which was combined with other drugs that can increase potassium without proper monitoring of the serum level (16.67%). In Pondok Kopi Islamic Hospital, Beers 2019 criteria can describe PIMs data better than the STOPP version 2 2016 due to data availability. Clinician and pharmacist collaboration is also needed in formulating the critical supporting data.
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