褐色脂肪组织:治疗胰岛素抵抗的潜力,明天的新希望

S. Arefhosseini, Sepideh Alijani
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引用次数: 2

摘要

众所周知,白色脂肪组织是一种分泌多种激素的内分泌器官,本文简单介绍了棕色脂肪组织(brown fat tissue, BAT)的生理学概念,棕色脂肪组织是一种极其活跃的内分泌器官,在中间代谢中起着各种代谢活性作用。褐色脂肪组织的生理功能有助于细胞的能量产生部分。它的数量是罕见的,大约130克,这意味着哺乳动物的重要特征。能量消耗的增加可能是通过激活BAT来达到的目的,似乎将来会减轻体重,这需要大量的基础研究来促进其发生[1]。棕色脂肪组织产生热量,对人体代谢具有重要意义[2,3]。棕色脂肪组织在超重和肥胖人群中减少,激活棕色脂肪组织可能有助于减轻体重和与体重相关的代谢紊乱,如胰岛素抵抗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Brown fat tissue: Therapeutic potential for insulin resistance, new hopes for tomorrow
OPEN ACCESS The well recognized white adipose tissue is an endocrinal organ secreting various hormones and this article simply indicates to the physiologic concepts brown fat tissues (BAT) which are extremely active endocrine organs and play various metabolic active roles in intermediate metabolism. The physiologic function of Brown adipose tissues contributes to energy-producing parts of the cell. Its amount is rare up to approximately one hundred and thirty gram and implies important characteristics for mammals. An increase in energy expenditure could be an aim by activation of BAT, seems futurity to reduce body weight that needs a vast majority of fundamental research to facilitate its occurrence [1]. Brown fat tissue generates heat and has valuable importance for human metabolism [2,3]. Brown fat tissue is decreased in overweight and obese people and possibly activating brown fat tissue might help for reducing weight and weight-related metabolic disorders like insulin resistance.
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