白参叶沸水(tristiopsis Merguensis (Griff.))作为降血胆固醇中药的有效性

M. Sudirman, Kartika, Rachmawati Felani Djuria, A. Pratiwi
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引用次数: 0

摘要

白拉望叶(tristiopsismerguensis Griff.)是一种药用植物,用于降低邦加勿里东群岛省马来人的血液胆固醇水平。本研究旨在发现白拉望叶作为传统药物在邦加勿里东群岛马来族中降低血胆固醇的有效性及其对肝脏和肾脏的安全性。这是一项前后测试设计的临床观察研究,于2018年8月至12月进行,共有30名受试者。只有一个组,受试者采用非随机抽样的方式选择。纳入标准:总胆固醇水平> 200mg /dl和<350mg/dl的高胆固醇血症患者。排除标准:伴有并发症的血脂异常患者。双变量分析中使用夏皮罗威尔克检验。平均血液总胆固醇水平显示出降低的效果,并在试验前和试验后给药的显著差异。受试者有肝功能受损的副作用,表明SGOT的平均值增加。受试者的肾功能紊乱,这表明平均肌酐和尿素值增加,但仍不到两倍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effectiveness of The Use of Pelawan Leaf Boiled Water (Tristaniopsis Merguensis (Griff.) as a Traditional Medicine for Reducing Blood Cholesterol
Pelawan leaf (TristaniopsisMerguensis Griff.) is a medicinal plant used to reduce blood cholesterol levels used by Malays ethnic in the Bangka Belitung Islands province. This study aimed to find the effectiveness of the Pelawan leaf as a traditional medicine for reducing blood cholesterol and its safeness for liver and kidneys among Malays ethnic in Bangka Belitung Islands Province. This is a pre-post test design clinical observation study that was conducted from August to December 2018, with 30 subjects. There is only one group, and the subjects were chosen by non-random sampling. The inclusion criteria: hypercholesterolemia patients with total cholesterol levels> 200 mg/dl and <350mg/dl. And exclusion criteria: people with dyslipidemia with complications. The Shapiro Wilk test is used in bivariate analysis. The mean total blood cholesterol level showed a decrease in effect and a significant difference between the pre-test post-test administration of the Pelawan leaf boiled water. The subjects had side effects of impaired liver function indicated by an increase in the mean value of SGOT. The subjects affected kidney function disorders, which indicated an increase in the average creatinine and urea values, but still less than twice.
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