超侵袭性观胸病的癌变问题

M. Shvedsky, V. Bychkov, V. V. Matvienko, O.G. Solovyova, R. I. Duboshinsky, D.A. Vagina
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引用次数: 0

摘要

回顾性分析国外PubMed文献,探讨超侵袭性胆胸病对胆管细胞癌可能发展的影响。经过研究,我们得出结论,O. Felineus在癌变的起始阶段没有切入点,而是作为胆管癌的促进剂(СС),因此如果没有其他致癌物和增加胆管癌发生概率的特定因素(慢性炎症,自由基)的额外影响,则不能认为是该疾病的主要原因。关键词:超侵袭性蛇胸蚴病,寄生,免疫系统,癌变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
On the question of carcinogenesis in superinvasive opisthorchiasis
Retrospective analysis of foreign literature present in PubMed was carried out with the purpose to define possible influence of superinvasive opisthorchiasis on possible development of cholangiocellular carcinoma. After the research we conclude that O. Felineus doesn’t have an entry point during the initiation stage of carcinogenesis but rather acts as a promotor of cholangiocarcinoma (СС), and therefore cannot be considered a primary cause of the disease without additional influence of another carcinogens and specific factors that increase the probability of cholangiocarcinoma development (chronic inflammation, free radicals). Keywords: superinvasive opisthorchiasis, parasitism, immune system, carcinogenesis.
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