非镇静性抗组胺药治疗儿童变应性鼻炎的临床经验。

Rhinology. Supplement Pub Date : 1992-09-01
S F Wood
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引用次数: 0

摘要

本文回顾了所有涉及阿司咪唑在儿童中使用的临床研究。共有21项研究(1008例患者)考虑了季节性变应性鼻炎、多年性鼻炎和各种过敏性疾病的适应症。对照物为安慰剂和其他抗组胺药,如氯苯那敏和特非那定。阿司咪唑和其他抗组胺药对这些疾病的治疗有效,用阿司咪唑治疗的结果更有利。阿司咪唑在实验室数据和无副作用方面表现得非常令人满意。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical experience with non-sedating antihistamines in paediatric allergic rhinitis.

This paper reviews all clinical studies involving the use of astemizole in children. The indications of seasonal allergic rhinitis, perennial rhinitis and various allergic disorders were considered in a total of 21 studies (1,008 patients). Reference compounds were placebo and other antihistamines, such as chlorpheniramine and terfenadine. Astemizole and other antihistamines were effective in the treatment of these disorders with a more favourable result for those treated with astemizole. Astemizole appeared very satisfactory as regards laboratory data and absence of side effects.

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