镰状细胞病儿童钴胺素缺乏:使用氧化亚氮气体的意外风险

Joint Program: Section on Integrative Medicine and Section on Emergency Medicine Pub Date : 2021-02-24 DOI:10.1542/PEDS.147.3_MEETINGABSTRACT.276

R. Krieger, L. Brown, C. Dampier, F. Harris, Shaminy Manoranjithan, Reshika D Mendis, N. Cooper, J. Figueroa, C. Morris

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摘要

背景:儿童镰状细胞病(SCD)中钴胺素(B12)缺乏症的患病率尚不清楚，然而据报道，成年SCD患者中有18%缺乏B12，而非SCD患者中有10%缺乏B12 (Kamineni 2006)。SCD中b12缺乏症的较高频率可能是由于较高的溶血率、红细胞周转率和叶酸缺乏症。一氧化二氮气体通常用于牙科手术，是法国镰状相关血管闭塞性疼痛的标准治疗方法。最近我们……

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Cobalamin Deficiency In Children With Sickle Cell Disease: An Unanticipated Risk For Use Of Nitrous Oxide Gas

Background: The prevalence of cobalamin (B12) deficiency in children with sickle cell disease (SCD) is unknown, however B12-deficiency has been reported in 18% of SCD-adults versus 10% in patients without SCD (Kamineni 2006). A higher frequency of B12-deficiency in SCD may be due to higher rates of hemolysis, erythrocyte turnover and folate deficiency. Nitrous oxide gas is commonly used for dental procedures and is standard therapy for sickle-related vaso-occlusive-pain in France. Recently we …

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Joint Program: Section on Integrative Medicine and Section on Emergency Medicine

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