蝎子毒液及其对病原菌的适应性作用:以1876和大肠杆菌为例

Dumas Gálvez, Eleodoro Bonilla, Carlos Vega
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引用次数: 0

摘要

蝎子毒液已被广泛研究,主要是针对人类健康的应用,有强有力的证据表明它具有抗菌特性。然而,对这些抗菌特性适应性作用的生态学研究大多被忽视。在此,本研究调查了1876年的蝎子Centruroides granosus Thorell(蝎子:Buthidae)的毒液是否对注射了致病性大肠杆菌菌株的蟋蟀提供保护。与对照组(磷酸盐缓冲盐水(PBS)注射)和注射毒液的蝎子相比,在食用被污染的猎物时不注射毒液会降低蝎子的存活率。注射毒液的蝎子在食用被污染的猎物时并没有表现出较低的存活率,与他们自己的对照组相比,被阻止或被允许注射毒液的蝎子的存活率没有差异。总之,研究结果强调了蝎子在对付潜在危险猎物时,毒液的适应性优势。讨论了这些发现的意义,这项工作旨在鼓励更多被忽视的蝎子和其他节肢动物毒液进化生态学领域的工作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Scorpion venom and its adaptive role against pathogens: a case study in Centruroides granosus Thorell, 1876 and Escherichia coli
Scorpion venoms have been studied extensively, mostly aimed at applications for human health, with strong evidence of antimicrobial properties. However, ecological studies on the adaptive role of these antimicrobial properties have been mostly neglected. Here, this study investigated in the scorpion Centruroides granosus Thorell, 1876 (Scorpiones: Buthidae) whether the venom provided protection against the consumption of crickets injected with a pathogenic strain of the bacteria Escherichia coli. Preventing venom injection when consuming contaminated prey decreased scorpion survival as compared to their controls (phosphate-buffered saline (PBS) injection) and scorpions that injected the venom. Scorpions that injected the venom did not show lower survival when consuming contaminated prey as compared to their own control, and there was no difference in survival for the controls of scorpions that were prevented or allowed to inject the venom. Altogether, the results highlight the adaptive benefit of the venom for scorpions when coping with potentially hazardous prey. The implications of the findings are discussed, and this work seeks to encourage more work on the neglected field of venom evolutionary ecology of scorpions and other arthropods.
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