用药手册对2型糖尿病患者依从率的影响分析

Atika Wahyu Puspitasari, R. Andrajati, A. Bahtiar
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摘要

糖尿病(DM)是一种以血糖升高为特征的慢性代谢性疾病。2型糖尿病患者不坚持治疗导致血糖控制不良,增加疾病并发症的风险。教育是提高服药依从性的方法之一。印度尼西亚公共初级卫生保健的药剂师数量有限,导致教育无法有效开展,因此有必要寻找其他替代教育,如药物小册子。本研究旨在评估药物手册对2型糖尿病患者依从率参数的影响。这是2012年1月至6月在Depok的Bakti Jaya初级保健中心进行的实验前和前瞻性研究。对30例2型糖尿病患者进行了方便抽样,并对其进行了用药说明书的发放。8周干预前后测量8项Morisky药物依从性量表(MMAS-8)值和糖化血红蛋白百分比(HbA1C)。采用HbA1C配对t检验和MMAS-8 Wilcoxon检验分析结果。研究结果显示,干预8周前后HbA1C、MMAS-8值差异有统计学意义(p < 0.05)。结果表明,通过用药手册进行糖尿病教育,可有效提高患者的服药依从性。该研究还发现,Morisky评分较低的患者的HbA1C测量值也较低。关键词:MMAS-8,糖化血红蛋白,依从性,血糖,2型糖尿病,小册子,药师
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE EFFECTIVENESS ANALYSIS OF MEDICATION BOOKLET ON ADHERENCE RATE IN TYPE 2 DIABETES MELLITUS PATIENTS
Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by elevation of blood glucose concentration. Non-adherence to diabetes treatment in type 2 DM patients leads to poor glucose control and increases the risk of disease complications. Education is one of the ways to increase medication adherence. Limitation of pharmacists in public primary health care in Indonesia led to education could not be done effectively so that it was necessary to find other alternatives education such as medication booklet. This study was undertaken to evaluate the effect of a medication booklet on adherence rate parameters, in type 2 diabetic patients. This was pre-experimental and prospective study conducted at Bakti Jaya primary care, Depok from January to June 2012. A convenience sample of 30 type 2 diabetic patients was studied to receive medication booklet. The value of The 8-item Morisky Medication Adherence Scale (MMAS-8) and percentage of glycosylated haemoglobin (HbA1C) were measured before and after the 8-week intervention. The results were analyzed by paired t-test for HbA1C and Wilcoxon test for MMAS-8. The research result  showed that there were significant differences (p < 0.05) of the value of HbA1C and MMAS-8 between before and after the 8-week intervention. It indicated that a diabetes education by medication booklet, was effective enhancing their medication adherence. This study also found that patients with a lower score on the Morisky scale had a lower HbA1C measurement. Keywords : MMAS-8, HbA1C, adherence, blood glucose, type 2 diabetes mellitus, booklet, pharmacist
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