从肺软体动物的神经节中分离的抑菌肽类似物。

Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology Pub Date : 1992-02-01

T Ikeda, Y Yasuda-Kamatani, H Minakata, P T Kenny, K Nomoto, Y Muneoka

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摘要

1. 从非洲巨螺(Achatina fulica)的神经节中分离出10条抑制Mytilus ABRM相收缩的肽。2. 其中7个肽被证明是六肽，具有-Pro-Xaa-Phe-Val-NH2作为共同结构，这是以前被证明是贻贝螺抑制肽(MIPs)的特征。3.其余三种为五肽，每一种由- gly - arg - arg -连接的两个与mip相关的六肽组成。

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Mytilus-inhibitory peptide analogues isolated from the ganglia of a pulmonate mollusc, Achatina fulica.

1. Ten peptides that showed an inhibitory effect on phasic contraction of the ABRM of Mytilus were isolated from the ganglia of the African giant snail, Achatina fulica. 2. Seven of the peptides were shown to be hexapeptides having -Pro-Xaa-Phe-Val-NH2 as a common structure, which was previously shown to be a characteristic of Mytilus inhibitory peptides (MIPs). 3. The remaining three were pentadecapeptides, each of which consisted of two MIP-related hexapeptides linked by -Gly-Arg-Arg-.

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Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology

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