Portable Analytical Device for Bedside Monitoring of the Functional State of the Hemostasis System

The paper considers the issues of practical implementation of the portable analytical device for bedside monitoring of the functional state of the hemostasis system using whole blood. The design of devices for evaluating the functioning of the hemostasis system based on whole blood analysis is a promising area of research and development in the field of medical technology, as it can significantly reduce the time of one test. The block diagram of the device, basic solutions for hardware and software components, as well as the layout of the device are considered. Various designs of disposable blood sampling cuvettes are presented, and the choice of a cuvette for a commercial device is discussed. The device was used to assess vascular-platelet hemostasis of volunteers in real time. The results obtained demonstrated a high degree of correlation with the standard method used to assess the system of regulation of the aggregate state of blood in clinical practice. The main advantage of the developed system is the possibility of studying whole blood in the Point-of-Care Test mode (at the patient's bedside).