罗非鱼(Oreochromis aureus)胶原蛋白医用生物材料

David R. Valenzuela-Rojo, J. López‐Cervantes, D. Sánchez‐Machado
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引用次数: 14

摘要

胶原蛋白是一种具有生物相容性和可生物降解性的天然高分子材料,广泛应用于医药产品和营养补充剂中。胶原蛋白是一种支持多种组织的纤维蛋白,其主要结构是由甘氨酸-脯氨酸-羟脯氨酸重复单位构成的。传统的胶原蛋白来源,如牛皮、猪皮或鸡粪,由于动物传播疾病的危险,限制了它们的使用。因此,海洋动物是提取胶原蛋白的另一种选择。Oreochromis aureus的俗称是罗非鱼,被广泛养殖,作为冷冻鱼片出售。在其加工过程中,会产生大量富含胶原蛋白的废弃物。因此,本书章节的目的是证明罗非鱼皮肤作为生物材料的胶原蛋白的替代来源的潜力。在文献综述的基础上,介绍了罗非鱼皮肤胶原蛋白在医用敷料中提取和表征的实验结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tilapia (Oreochromis aureus) Collagen for Medical Biomaterials
Collagen is a natural polymer widely used in pharmaceutical products and nutritional sup- plement due to its biocompatibility and biodegradability. Collagen is a fibrous protein that supports various tissues, and its primary structure is formed by repeated units of glycine- proline-hydroxyproline. Traditional sources of collagen, such as bovine and pig skins or chicken waste, limit their use due to the dangers of animal-borne diseases. Thus, marine animals are an alternative for the extraction of collagen. The common name of Oreochromis aureus is tilapia, widely cultivated for sale as frozen fillets. During its processing, a large amount of collagen-rich wastes are generated. Therefore, the objective of this book chapter is to prove the potential of tilapia skin as an alternative source of collagen for the elaboration of biomaterials. Additionally to the literature review, experimental results of the extraction and characterization of tilapia skin collagen for use in medical dressings are presented.
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