CpG甲基化的转录抑制作用。

R Meehan, J Lewis, S Cross, X Nan, P Jeppesen, A Bird
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引用次数: 91

摘要

哺乳动物DNA甲基化与转录抑制和核酸酶抗性染色质有关。在这篇综述中,我们讨论了这些影响是如何通过结合甲基化DNA的蛋白质介导的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transcriptional repression by methylation of CpG.

Methylated DNA in mammals is associated with transcriptional repression and nuclease resistant chromatin. In this review we discuss how these effects may be mediated by proteins that bind to methylated DNA.

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