“临界红细胞压积”:一个因人而异的数字。

P Lundsgaard-Hansen
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引用次数: 0

摘要

在我看来,“临界红细胞压积”的问题可以概括为五个论点:首先,不能将任何单一的血红蛋白或红细胞压积值标记为普遍可接受的值,原因是,其次,适当的值在患者之间不同,有时在个体病程的不同阶段也不同,例如在手术期间和术后期间。第三,正常范围内的血红蛋白或红细胞压积构成了一个天然的缓冲,防止非血红蛋白引起的对氧气供应的侵蚀。有意操纵这一缓冲需要仔细评估潜在的利益与风险。第四,在其他方面状况良好的患者可容忍血红蛋白或红细胞压积分别低于10g /dl或30%,降至约8g /dl或25%,但耐受并不一定等同于最佳。第五,最依赖“血红蛋白缓冲”的病人是那些必须在没有重症监护病房监测设施的情况下克服困难的人,例如在只有初级保健设备的外围医院。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The 'critical hematocrit': a figure differing from patient to patient.

In my opinion, the problem of a 'critical hematocrit' can be summarized in five contentions: First, it is inadmissible to label any single hemoglobin or hematocrit value as being generally acceptable, the reason being, second, that the adequate values differ between patients and sometimes also between various stages of their individual course--for instance during the intra- and the postoperative period. Third, a hemoglobin or hematocrit within the normal range constitutes a natural buffer against encroachments upon the oxygen supply from non-Hb causes. Intentional manipulation of this buffer requires a careful assessment of potential benefits vs. risks. Fourth, a patient in otherwise perfect condition tolerates a hemoglobin or hematocrit below 10 g/dl or 30%, respectively, down to approximately 8 g/dl or 25%- but tolerance is not necessarily equivalent to an optimum. And fifth, the patient most dependent on his 'hemoglobin buffer' is the individual who has to overcome troubles without the monitoring facilities of an intensive care unit, for instance in the peripheral hospital equipped only for primary care.

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