Transsphenoidal pituitary surgery effects on obstructive sleep apnea in patients with acromegaly: a systematic review and meta-analysis

Obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of partial or complete obstruction of the upper airway during sleep.1 In general, OSAS is associated with upper airway abnormalities, including tonsil and adenoid hypertrophy, palatal webbing, nasal obstruction, retrognathia, macroglossia, and laryngeal abnormalities.2,3,4 Symptoms like sleepness and laryngopharyngeal reflux are also observed.2,3,4 The narrowing of the upper airway, along with the increased airway compliance, allows for the excessive collapsibility of the airway during sleep. (Is there a source for citation here?)