血红蛋白色素:在血红蛋白降解过程中合成的一种生物晶体

Biopolymers Online Pub Date : 2002-10-30 DOI:10.1002/3527600035.BPOL9007

D. Sullivan

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引用次数: 40

摘要

简介疟疾疟疾发病机制血红蛋白降解历史概述色素与疟疾色素关联蚊子与疟原虫生命周期化学结构发生功能血色素结构分析早期纯化与血吸虫色素比较血色素缺乏蛋白质铁氧配位键顺磁性血色素血色素生化形成血色素福尔马林色素其他寄生虫色素疟原虫蛋白起始色素对血色素形成的抑制免疫调节血色素对白细胞功能的干扰白细胞色素作为预后指标专利展望与展望关键词:血红素;铁;原卟啉IX。恶性疟原虫;疟疾色素;疟原虫色素;喹啉;化疗;β血色素;血红素的聚合物;裂体吸虫属;Haemoproteus;疟疾;免疫力;福尔马林色素

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Hemozoin: a Biocrystal Synthesized during the Degradation of Hemoglobin

Introduction Malaria Malaria Pathogenesis Hemoglobin Degradation Historical Outline Pigment Associates with Malaria Pigment Links Mosquito to Plasmodium Life Cycle Chemical Structure Occurrence Function of Hemozoin Structure of Hemozoin Analysis of Early Purifications Comparison with Schistosomal Pigment Hemozoin Lacks Protein The Iron–Oxygen Coordinate Bond Paramagnetic Hemozoin Biochemical Formation of Hemozoin Formalin Pigment Other Parasite Pigments Plasmodium Protein Initiation of Pigment Inhibition of Hemozoin Formation Immune Modulation of Hemozoin Perturbation of Leukocyte Function Leukocyte Pigment as a Prognostic Indicator Patents Outlook and Perspectives Keywords: Heme; iron; protoporphyrin IX. Plasmodium falciparum; malarial pigment; hemozoin; quinoline; chemotherapy; β-hematin; heme polymer; Schistosoma; Haemoproteus; malaria; immunity; formalin pigment

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Biopolymers Online

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