怀孕期间血糖酮症酸中毒:比你想象的更常见

I. Sapantzoglou, A. Psarris, P. Perros, A. Varthaliti, P. Antsaklis, M. Theodora, M. Syndos, G. Daskalakis
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引用次数: 0

摘要

背景:糖源性酮症酸中毒是一种罕见的代谢性酸中毒,伴有酮体生成增加和血清葡萄糖正常。当它发生在怀孕期间,它可能导致不利的母婴结局。妊娠本身是一种致糖尿病状态,即使在相对较短的饥饿期后,也可能使患者易患酮症酸中毒,因此,需要高度怀疑才能做出诊断并制定管理计划。病例介绍:我们报告一例糖尿病酮症酸中毒在双胎妊娠,发生在中期妊娠,需要及时和积极的管理,最终需要早期分娩,由于先兆子痫的发展。讨论/结论:妊娠期血糖酮症酸中毒的生理病理及处理方法,以避免该疾病可能并发的母胎风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Euglycaemic ketoacidosis during pregnancy: More common than you think
Background: Euglycaemic ketoacidosis is a rare type of metabolic acidosis, with increased production of ketonic bodies and normal serum glucose. When it occurs during pregnancy, it might lead to adverse maternal and fetal outcomes. Pregnancy itself is a diabetogenic state that might predispose the patient to develop ketoacidosis following even relatively short periods of starvation and as such, a high index of suspicion is required for the diagnosis to be made and for the management plan to be established. Case presentation: We present a case of euglycaemic ketoacidosis in a twin pregnancy, which occurred in the second trimester, necessitating prompt and aggressive management, that eventually required early delivery due to the development of preeclampsia. Discussion/Conclusion: The physiology and pathology of euglycaemic ketoacidosis during pregnancy and the management required to avoid the potential maternal and fetal risks that such a condition might be complicated with.
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