{"title":"斯里兰卡成人T细胞淋巴瘤/白血病伴肾浸润1例","authors":"Somawardana Uabp, Gunasinghe R, S. S, Pieris Dc","doi":"10.47829/acmcr.2021.7803","DOIUrl":null,"url":null,"abstract":"Adult T Cell Leukaemia/Lymphoma (ATLL) is a rare T cell lymphoproliferative disease associated with Human T Cell Lym-photropic Virus-1 (HTLV1) endemic in some parts of the world and therefore has a distinct demographic distribution. There are no cases of ATLL reported in Sri Lanka thus far hence this is the first reported case. Renal parenchymal infiltration in ATLL is ex - tremely rare. Due to the rarity of the disease, evidence-based standard therapeutic options are lacking. The outcome of patients with ATLL is poor, particularly in the relapsed and refractory settings. Here we report a case of ATLL with renal involvement that initially responded to combined chemotherapy but later regressed to refractory disease with poor response to combined immunotherapy and antiviral therapy.","PeriodicalId":380321,"journal":{"name":"Annals of Clinical and Medical Case Reports","volume":"86 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Adult T Cell Lymphoma/Leukaemia with Renal Infiltration: A Case Report from Sri Lanka\",\"authors\":\"Somawardana Uabp, Gunasinghe R, S. S, Pieris Dc\",\"doi\":\"10.47829/acmcr.2021.7803\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Adult T Cell Leukaemia/Lymphoma (ATLL) is a rare T cell lymphoproliferative disease associated with Human T Cell Lym-photropic Virus-1 (HTLV1) endemic in some parts of the world and therefore has a distinct demographic distribution. There are no cases of ATLL reported in Sri Lanka thus far hence this is the first reported case. Renal parenchymal infiltration in ATLL is ex - tremely rare. Due to the rarity of the disease, evidence-based standard therapeutic options are lacking. The outcome of patients with ATLL is poor, particularly in the relapsed and refractory settings. Here we report a case of ATLL with renal involvement that initially responded to combined chemotherapy but later regressed to refractory disease with poor response to combined immunotherapy and antiviral therapy.\",\"PeriodicalId\":380321,\"journal\":{\"name\":\"Annals of Clinical and Medical Case Reports\",\"volume\":\"86 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Clinical and Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47829/acmcr.2021.7803\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Clinical and Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47829/acmcr.2021.7803","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Adult T Cell Lymphoma/Leukaemia with Renal Infiltration: A Case Report from Sri Lanka
Adult T Cell Leukaemia/Lymphoma (ATLL) is a rare T cell lymphoproliferative disease associated with Human T Cell Lym-photropic Virus-1 (HTLV1) endemic in some parts of the world and therefore has a distinct demographic distribution. There are no cases of ATLL reported in Sri Lanka thus far hence this is the first reported case. Renal parenchymal infiltration in ATLL is ex - tremely rare. Due to the rarity of the disease, evidence-based standard therapeutic options are lacking. The outcome of patients with ATLL is poor, particularly in the relapsed and refractory settings. Here we report a case of ATLL with renal involvement that initially responded to combined chemotherapy but later regressed to refractory disease with poor response to combined immunotherapy and antiviral therapy.