Rheoophthalmography Used for the Analysis of Blood Flow in the Posterior Part of the Eye

The paper is aimed at developing a new rheoophthalmography (ROG) technique able to measure electrical impedance signals of patients with primary open-angle glaucoma (POAG), which could facilitate early diagnostics of the disease and the differentiation of its stages. We used a technique of electrode positioning differing from the transpalpebral ROG technique used previously. Specifically, we changed the distance between the measuring electrodes and their location pattern: the axis of symmetry was rotated 90° relative to that used in the transpalpebral technique and located vertically rather than horizontally. This technique was applied to ROG signals of 32 patients (42 eyes) aged 67.7 years averagely. Of these, 6 patients (10 eyes) average aged 62.7 years had stage I (early) POAG or suspected POAG; 13 patients (17 eyes) average aged 69.4 years had stage II (developed) POAG; 10 patients (12 eyes) average aged 70.0 years had stage III (advanced) POAG; 3 patients (3 eyes) average aged 69.3 years had stage IV (terminal) POAG. The results of this study confirmed the feasibility of the above technique for ROG signal registration. The recorded signals are informative for quantitative assessment of blood flow in the posterior part of the eye, which enables early POAG diagnostics and differentiation between POAG stages.