Evans蓝:viii因子诱导的血小板凝集的特异性抑制剂。

Thrombosis et diathesis haemorrhagica Pub Date : 1975-12-15

E P Kirby

{"title":"Evans蓝:viii因子诱导的血小板凝集的特异性抑制剂。","authors":"E P Kirby","doi":"","DOIUrl":null,"url":null,"abstract":"Low concentrations of Evans Blue (less than 1 muM) inhibit the agglutination of formalin-treated platelets by bovine Factor VIII or by human Factor VIII in the presence of the antibiotic ristocetin. Evans Blue is a specific inhibitor of this reaction and acts by inhibiting the binding of Factor VIII to the platelet surface.","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 3","pages":"770-9"},"PeriodicalIF":0.0000,"publicationDate":"1975-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evans blue: a specific inhibitor of factor VIII-induced platelet agglutination.\",\"authors\":\"E P Kirby\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Low concentrations of Evans Blue (less than 1 muM) inhibit the agglutination of formalin-treated platelets by bovine Factor VIII or by human Factor VIII in the presence of the antibiotic ristocetin. Evans Blue is a specific inhibitor of this reaction and acts by inhibiting the binding of Factor VIII to the platelet surface.\",\"PeriodicalId\":23068,\"journal\":{\"name\":\"Thrombosis et diathesis haemorrhagica\",\"volume\":\"34 3\",\"pages\":\"770-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1975-12-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Thrombosis et diathesis haemorrhagica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Thrombosis et diathesis haemorrhagica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

低浓度的埃文斯蓝(小于1mum)抑制福尔马林处理过的血小板通过牛因子VIII或人因子VIII在抗生素立斯托霉素存在下的凝集。Evans Blue是该反应的特异性抑制剂，通过抑制因子VIII与血小板表面的结合而起作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Evans blue: a specific inhibitor of factor VIII-induced platelet agglutination.

Low concentrations of Evans Blue (less than 1 muM) inhibit the agglutination of formalin-treated platelets by bovine Factor VIII or by human Factor VIII in the presence of the antibiotic ristocetin. Evans Blue is a specific inhibitor of this reaction and acts by inhibiting the binding of Factor VIII to the platelet surface.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Thrombosis et diathesis haemorrhagica

自引率

0.00%

发文量