{"title":"铥-170近距离治疗源的发展及其在大鼠治疗中的应用","authors":"I. Levinger, G. Shani","doi":"10.4172/2155-9619.1000292","DOIUrl":null,"url":null,"abstract":"Experimental work where Tm-170 LDR seeds and one HDR source were used to treat cancer on rats is described. Experiments were done with Lewis rats, carrying tumor developed from implantation of CNS-1 Rat Brain Tumor Astrocytoma cells, under the thigh skin. 75% of both HDR and LDR treated rats were completely cured. I-125 seeds experiments were done as a control, only 8.3% were cured with a similar photon dose. The dose due to beta radiation is very significant and was the main reason for the treatment success.","PeriodicalId":302578,"journal":{"name":"Journal of Nuclear Medicine and Radiation Therapy","volume":"106 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2016-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Development of Thulium-170 Brachytherapy Sources and Application inRats Treatment\",\"authors\":\"I. Levinger, G. Shani\",\"doi\":\"10.4172/2155-9619.1000292\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Experimental work where Tm-170 LDR seeds and one HDR source were used to treat cancer on rats is described. Experiments were done with Lewis rats, carrying tumor developed from implantation of CNS-1 Rat Brain Tumor Astrocytoma cells, under the thigh skin. 75% of both HDR and LDR treated rats were completely cured. I-125 seeds experiments were done as a control, only 8.3% were cured with a similar photon dose. The dose due to beta radiation is very significant and was the main reason for the treatment success.\",\"PeriodicalId\":302578,\"journal\":{\"name\":\"Journal of Nuclear Medicine and Radiation Therapy\",\"volume\":\"106 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-06-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Nuclear Medicine and Radiation Therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2155-9619.1000292\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nuclear Medicine and Radiation Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2155-9619.1000292","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Development of Thulium-170 Brachytherapy Sources and Application inRats Treatment
Experimental work where Tm-170 LDR seeds and one HDR source were used to treat cancer on rats is described. Experiments were done with Lewis rats, carrying tumor developed from implantation of CNS-1 Rat Brain Tumor Astrocytoma cells, under the thigh skin. 75% of both HDR and LDR treated rats were completely cured. I-125 seeds experiments were done as a control, only 8.3% were cured with a similar photon dose. The dose due to beta radiation is very significant and was the main reason for the treatment success.
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