抗nmda受体脑炎:一种神经精神疾病

Andac Topkan, S. Bilen, E. Eruyar, Y. Karadag
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引用次数: 3

摘要

抗nmda受体脑炎是一种自身免疫性脑炎,表现为急性或亚急性发作的精神症状、癫痫发作、自主神经功能障碍和运动障碍。这是一种最近才被发现的疾病,大约20%的患者可能会死亡,并且可以通过积极的免疫抑制治疗而恢复,没有任何后遗症。颅磁共振成像可观察到多灶性、非特异性皮层下白质病变。由于它大多有副肿瘤病因,诊断后筛查恶性肿瘤是至关重要的。它的诊断是非常重要的,因为它将导致早期诊断可能的恶性肿瘤。本文报告一例应用于我们门诊的神经精神临床图像嘈杂,经评估后被诊断为抗nmda受体脑炎,并经完全康复治疗的病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anti-NMDA receptor encephalitis: a neuropsychiatric entity -
Anti-NMDA receptor encephalitis: a neuropsychiatric entity AntiNMDA receptor encephalitis is a form of autoimmune encephalitis which manifests itself with acute or subacute onset psychiatric symptoms, seizures, autonomic dysfunction, and movement disorders. It is a rather recently described form which may progress fatal at about 20%, and which may recover with aggressive immunosuppressive treatment without any sequela. Multifocal, non-specific, subcortical white matter lesions can be observed in cranial magnetic resonance imaging. Since mostly it has paraneoplastic etiology, it is crucial to screen for malignancies after the diagnosis. Its diagnosis is very important, because it will lead early diagnosis of a possible mallignancy. In the present article, a case which applied to our outpatient clinic with noisy neuropsychiatric clinical picture, and was diagnosed with anti-NMDA receptor encephalitis after evaluations, and treated with complete recovery, was presented.
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