第六章。纳米粒子-蛋白质相互作用对生物检测的影响

Nanoparticle–Protein Corona Pub Date : 2019-07-26 DOI:10.1039/9781788016308-00163

Kavita Dubey, Onila Lugun, A. Pandey

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引用次数: 1

摘要

纳米颗粒上的蛋白质冠状体不仅具有广泛的应用前景，但也显示出各种局限性。当纳米颗粒与生物流体接触时，一系列生物分子，包括脂质和蛋白质，会吸附在纳米颗粒的表面，形成蛋白质冠状体。因此，在本章中，我们将回顾涉及纳米颗粒和蛋白质冠相互作用的各种因素，以及这些相互作用在生物影响和分析方面的利弊。

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CHAPTER 6. Impact of Nanoparticle–Protein Interactions on Biological Assays

Protein coronas on nanoparticles not only bring a wide range of applications, but also show various limitations. When nanoparticles come into contact with biological fluids, a range of biomolecules, including lipids and proteins, adsorb on the surfaces of the nanoparticles and form protein coronas. Thus, in this chapter, we will review various factors involved in the interactions of nanoparticles and protein coronas, and the pros and cons of these interactions in reference to biological impacts and assays.

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Nanoparticle–Protein Corona

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