益生菌漱口水对牙菌斑积累的影响:一项随机对照试验

P. Thakkar, Imranulla, P. Kumar, G. Prashant, B. Sakeenabi, V. Sushanth
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引用次数: 9

摘要

简介:龋齿和炎症性牙周病是由许多不同的细菌积累形成牙菌斑引起的,牙菌斑是一种自然获得的细菌生物膜,生长在牙齿上。牙周病是最普遍的口腔疾病之一,影响超过50%的印度社区。材料和方法:对来自达万热市一家旅馆的90名年龄在13至15岁之间的学童进行了为期两个月的随机对照试验。将90名符合纳入和排除标准的受试者随机分为安慰剂组、氯己定组和益生菌组。在基线(0天)、第15天(干预后14天)和3周(停止干预后)记录斑块评分。统计学分析采用单因素方差分析和配对“t”检验,P值< 0.05为有统计学意义。结果:两组在基线时无统计学差异。在第15天和3周后,安慰剂组的斑块评分明显高于益生菌组。第15天和3周后,氯己定组斑块评分高于益生菌组,但差异无统计学意义。结论:干预14天后和停止干预3周后,益生菌漱口水对牙菌斑积累的抑制作用更明显。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of probiotic mouthrinse on dental plaque accumulation: A randomized controlled trial
Introduction: Dental caries and inflammatory periodontal diseases result from the accumulation of many different bacteria that form dental plaque, a naturally acquired bacterial biofilm that develops on the teeth. Periodontal diseases are one of the most prevalent oral diseases affecting more than 50% of Indian community. Materials and Method: A two months randomised controlled trial was conducted among ninety school children aged between 13 and 15 years, from a hostel located in Davangere city. The 90 study subjects who fulfilled inclusion and exclusion criteria were randomly divided into 3 groups namely Placebo, Chlorhexidine and Probiotic groups. Plaque scores were recorded at baseline (0 day), on 15 th day (after 14 days of intervention) and 3 weeks (after discontinuation of intervention). Statistical analysis was done using one way ANOVA and paired ' t ' test and P value less than 0.05 was considered statistically significant. Results: There was no statistically significant difference between groups at baseline. On 15 th day and after 3 weeks, plaque scores were significantly higher in placebo group compared to probiotic group. On 15 th day and after 3 weeks, plaque scores were higher in chlorhexidine group compared to probiotic group but difference was not statistically significant. Conclusion: Probiotic mouth rinse was more effective for inhibition of dental plaque accumulation after 14 days of intervention and also after 3 weeks of discontinuation of intervention.
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