单纯性煤矿工人尘肺中一氧化碳的肺弥散能力。

A Frans, C Veriter, L Brasseur
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摘要

本文测定了43名矿工和141名对照者静息时的肺一氧化碳弥散量(DLCO)及其两组分毛细血管血容量(Vc)和肺膜弥散量(DMCO),并建立了对照者的参考公式;在30名对照受试者和大多数矿工中,这些指标是在运动期间测量的。主要结果如下:单纯煤矿工人尘肺扩散指数平均略有下降;在休息和运动时,DMCO和Vc均有助于降低DLCO;单独来看,Vc比DMCO更常发生显著变化;在努力过程中,煤矿工人DLCO百分比的增加是正常的;运动期间的数据表明,吸烟习惯对降低DLCO的贡献大于尘肺病本身;最后,“针尖”型矿工的弥散指数低于微结节性混浊者,这种趋势在运动中更为明显。对这些发现进行了讨论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pulmonary diffusing capacity for carbon monoxide in simple coal workers' pneumoconiosis.

The lung diffusing capacity for carbon monoxide (DLCO single-breath) and its two components, the capillary blood volume (Vc) and the diffusing capacity of the membrane (DMCO) were measured at rest in 43 miners and 141 control subjects, the values in whom enabled reference formulae to be established; in 30 control subjects and in the majority of the miners these indices were measured during exercise. The main results are as follows: the diffusion indices are on average slightly decreased in simple coal workers' pneumoconiosis; both DMCO and Vc contribute to the lowering of DLCO, at rest and during exercise; individually Vc is more often significantly altered than DMCO; on effort the percentage increase of DLCO is normal in coal miners; the data during exercise suggest that smoking habit contributes more to lowering DLCO than does pneumoconiosis itself; lastly the diffusion indices are lower in miners with "pin-head" than those with micronodular opacities: this tendency is more pronounced during exercise. These findings are discussed.

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