L Fialip, M Payard, P Bastide, P Ralite, Y Teillard
{"title":"实验氯汞中毒中类似于羧羟肟酸-2(钠盐)分子的活性;染色体周期的重要性]。","authors":"L Fialip, M Payard, P Bastide, P Ralite, Y Teillard","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The carbo-hydroxamic-2 chromone acid (sodium salt) shows a higher protective action in vivo than in vitro against mercury chloride induced intoxications. The higher effect observed in vivo might be due to the activity itself of the chromone cycle which added up to that of the carbo-hydroxamic acid function. This latter alone appears in vitro. The antihyaluronidasic properties of this protective agent allow it to prevent the toxic substances to be diffused.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"8 6","pages":"347-52"},"PeriodicalIF":0.0000,"publicationDate":"1975-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Activities of molecules similar to carboxyhydroxamic acid chromone-2 (sodium salt) in experimental mercury chloride poisoning; importance of the chromone cycle].\",\"authors\":\"L Fialip, M Payard, P Bastide, P Ralite, Y Teillard\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The carbo-hydroxamic-2 chromone acid (sodium salt) shows a higher protective action in vivo than in vitro against mercury chloride induced intoxications. The higher effect observed in vivo might be due to the activity itself of the chromone cycle which added up to that of the carbo-hydroxamic acid function. This latter alone appears in vitro. The antihyaluronidasic properties of this protective agent allow it to prevent the toxic substances to be diffused.</p>\",\"PeriodicalId\":75837,\"journal\":{\"name\":\"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie\",\"volume\":\"8 6\",\"pages\":\"347-52\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1975-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Activities of molecules similar to carboxyhydroxamic acid chromone-2 (sodium salt) in experimental mercury chloride poisoning; importance of the chromone cycle].
The carbo-hydroxamic-2 chromone acid (sodium salt) shows a higher protective action in vivo than in vitro against mercury chloride induced intoxications. The higher effect observed in vivo might be due to the activity itself of the chromone cycle which added up to that of the carbo-hydroxamic acid function. This latter alone appears in vitro. The antihyaluronidasic properties of this protective agent allow it to prevent the toxic substances to be diffused.