细胞凋亡的细胞质和细胞核特征综述

Apoptosis and Beyond Pub Date : 2018-10-05 DOI:10.1002/9781119432463.CH1

H. Vitto, Juan P. Valencia, J. Radosevich

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引用次数: 1

摘要

凋亡诱导因子Apaf-1凋亡蛋白酶激活因子ATP三磷酸腺苷Bcl-2 b细胞淋巴瘤Bcl-2 BID bh3相互作用结构域死亡激动剂bp碱基对CAD caspase活化dna酶c- flip细胞flice抑制蛋白Chx环六甲素CsA环胞素A CTL细胞毒性T淋巴细胞细胞色素c DISC死亡诱导信号复合体死亡效应结构域内切酶D内切酶G内切酶G内质网FADDfas相关死亡结构域蛋白FasL脂肪酸合成酶配体FasR脂肪酸合成酶受体Gzm-A颗粒酶-a Gzm-B颗粒酶- b ICAD半胱天冬酶活化dna酶Kb千基酶抑制剂MEF小鼠胚胎成纤维细胞MOMP线粒体外膜通透性NK自然杀手OMM线粒体外膜PCD程序性细胞死亡PFN穿孔素

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General View of the Cytoplasmic and Nuclear Features of Apoptosis

AIF apoptosis-inducing factor Apaf-1 apoptotic protease activating factor-1 ATP adenosine triphosphate BA bongkrekic acid Bcl-2 B-cell lymphoma-2 BID BH3-interacting domain death agonist bp base pair CAD caspase-activated DNase c-FLIP cellular FLICE-inhibitory protein Chx cyclohexamide CsA cyclosporine A CTL cytotoxic T lymphocyte cyt c cytochrome c DISC death-inducing signal complex DED death effector domain endo D endonuclease D endo G endonuclease G ER endoplasmic reticulum FADD Fas-associated death-domain protein FasL fatty acid synthetase ligand FasR fatty acid synthetase receptor Gzm-A granzyme-A Gzm-B granzyme-B ICAD inhibitor of caspase-activated DNase Kb kilobase MEF mouse embryonic fibroblast MOMP mitochondrial outer-membrane permeabilization NK natural killer OMM outer mitochondrial membrane PCD programmed cell death PFN Perforin

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Apoptosis and Beyond

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