Vivostat®自体纤维蛋白密封剂在甲状腺手术中的应用

A. Pino, F. Frattini, Hui Sun, Daqi Zhang, Che‐Wei Wu, H. Kim, G. Dionigi
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引用次数: 1

摘要

简介:甲状腺手术后出血是一种罕见但可能危及生命和不可预测的并发症。因此,术中控制出血和止血至关重要。然而,实现这一目标的最有效、最具成本效益和最标准化的方法尚不清楚。本研究旨在评估使用Vivostat®止血系统(Vivostat A/S, Lillerød,丹麦)进行甲状腺全切除术(TT)和部分甲状腺切除术(PT)的疗效。方法:对良恶性疾病(多结节性甲状腺肿、Graves病、分化型甲状腺癌)患者行TT和PT治疗。主要终点是术后第1天排液量和需要再次干预的出血。次要终点包括手术时间和术后并发症(声带麻痹、低钙血症、血清肿、伤口感染)。结果:2020年10月至2020年12月,纳入56例患者;69.6%的女性;平均年龄49.5岁。平均24小时引流量为40毫升。无需重做手术。5.3%的病例存在血清瘤;无永久性声带麻痹或低钙血症。结论:本研究表明Vivostat®系统在甲状腺手术止血中是安全有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Use of Vivostat® Autologous Fibrin Sealant in Thyroid Surgery
Introduction: Post-thyroidectomy hemorrhage is a rare but potentially life-threatening and unpredictable complication of thyroid surgery. Therefore, intraoperative bleeding control and hemostasis are crucial. However, the most efficient, cost-effective, and standardized way to achieve this is not clear. This study aimed to evaluate the outcome of total thyroidectomy (TT) and partial thyroidectomy (PT) performed using the Vivostat® hemostatic system (Vivostat A/S, Lillerød, Denmark). Methods: Patients underwent TT and PT for benign and malignant diseases (multinodular goiter, Graves’ disease, differentiated thyroid carcinoma). The primary endpoint was 1st-day postoperative drain output and bleeding that required reintervention. Secondary endpoints included surgery duration and postsurgical complications (vocal fold palsy, hypocalcemia, seroma, wound infection). Results: Between October 2020 and December 2020, 56 patients were enrolled; 69.6% female; mean age 49.5 years. The mean 24-h drain output was 40 ml. No redo surgery was needed. Seroma was present in 5.3% of cases; no permanent vocal palsy or hypocalcemia was observed. Conclusion: This study shows that the Vivostat® system is both safe and effective for hemostasis during thyroid surgery.
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