传染病动力学建模和预测方法

A. Kosova, V. Chalapa, O. Kovtun
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摘要

介绍。尽管在公共卫生方面取得了巨大进展,但传染病是一个普遍问题,在发病率和死亡率方面造成了重大负担,感染的出现和再次出现及其动态往往是不可预测的。传染病建模与预测是流行病学决策的有效工具。本综述的目的是对传染病流行病学建模和预测方面的现有文献进行系统整理。材料与方法回顾了国内外不受发表日期限制的传染病建模与预测方面的文献。使用文本挖掘软件估计出版活动。结果和讨论。以下是最常见的建模方法:回归模型、时间序列模型、隔室模型、基于主体的模型和人工神经网络。有人指出,一些方法(回归分析、时间序列模型和人工神经网络)实施起来相对简单,但教授这些模型需要大量的历史数据。区隔模型在一定程度上不受这一限制,它们可以迅速发展,用于评估新发和再发感染,但它们的实施存在宿主群体异质性造成的问题。从技术角度来看,能够最完整地描述宿主种群异质性和其中的社会相互作用的基于主体的模型是极其复杂的。尽管存在各种用于疾病建模的数学算法,但在现场实践中对用户友好的疾病预测统计软件的需求仍然存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Methods for modellind and forecasting dynamics of infectious diseases
Introduction. Despite dramatic progress in public health, infectious diseases are common issue leading to significant burden in terms of morbidity and mortality, and emergence and re-emergence of infections and its dynamic are often unpredictable. Infectious diseases modelling and forecasting is effective instrument for policy making in epidemiology.The aim of the review is to systematize current literature on modelling and forecasting in infectious disease epidemiology.Materials and methods Literature review in field of modelling and forecasting of infectious diseases without restrictions by publication date was conducted. Publication activity was estimated using text mining software.Results and discussion. The following most common classes of modelling methods were marked: regression models, time-series models, compartmental models, agent-based models and artificial neural networks. It was noted that a number of methods (regression analysis, time-series models and artificial neural networks) are relatively simple to implement, but a considerable volume of history data is required for teaching these models. Compartmental models are partially free from this restriction, and they can be rapidly developed for assessment of emerging and reemerging infections, but their implementation presents issues caused by host population heterogeneity. Agent-based models that present most complete descriptions of host population heterogeneity and social interactions within it are extremely complex from the technical point of view.Conclusion. Despite the presence of various mathematical algorithms for disease modelling, the demand for user-friendly statistical software for disease forecasting in field practice is persist.
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