导致卵巢癌妊娠期的结膜和母性预后增加的因素

Efriyan Imantika, Shinta Prawitasari, Diah Rumekti Hadiati
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摘要

背景:妊娠合并卵巢癌存在妊娠期控制生长与肿瘤不控制生长之间的关系。妊娠的管理说明了最佳产妇治疗和胎儿生命之间的冲突,以获得最佳预后。发病率很低,但它发生在育龄妇女中,大多数发生在第一次怀孕。分析改善妊娠预后的因素和适当的管理对预防胎儿和产妇的发病率和死亡率是很重要的。目的:分析妊娠合并卵巢癌影响母婴预后的因素。方法:采用队列回顾性设计的描述性分析研究,选取2010年1月至2017年12月在日惹Sardjito医院就诊的妊娠合并卵巢癌患者的病历。所有统计分析均由计算机统计软件完成。结果:18例研究对象在Sardjito医院接受了8年的治疗。影响妊娠合并卵巢癌预后的因素有肿瘤诊断时的孕龄和上皮组织病理学类型。这些因素的预后优于早孕龄和临床非上皮组织病理学(p=0.18;Ci 95% 0.4-104.2;OR 6,5)和(p=0.29;Ci 95% 0.36-30.12;或3.28)。手术干预时机对妊娠预后的改善具有统计学意义和临床意义(p=0.02;或= 4.2)。结论:妊娠合并卵巢癌的因素在肿瘤诊断、上皮组织病理学分型及手术干预时机为II-III型时可改善胎儿及母体预后。最好的妊娠管理导致更好的预后。关键词:妊娠预后;卵巢癌;
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Faktor-Faktor yang Meningkatkan Prognosis Fetal dan Maternal pada Kehamilan dengan Kanker Ovarium
Background: Pregnancy complicated by ovarian cancer presents relation between controlled growth in pregnancy and uncontrolled growth in cancer. The management of pregnancy illustrate conflict between optimal maternal therapy and fetal life for best prognosis at all. The incidence was low but it occured in reproductive age women and most found in the first pregnancy. It is important to analyze factors that improve the prognosis of pregnancy and appropiate management to prevent fetal and maternal morbidity and mortality. Objectives: To analyze factor on pregnancy complicated by ovarian cancer that improve fetal and maternal prognosis Methods: This is descriptive analytic study with cohort retrospective design using medical records of pregnancy patient complicated by ovarian cancer that underwent treatment at Sardjito Hospital Yogyakarta on 2010, January till 2017, December. All statistical analysis were done by statistic software for computer. Results: There were 18 research subjek had been undergone treatment at Sardjito Hospital for 8 years. Factors on pregnancy related to prognosis of pregnancy complicated by ovarian cancer were late gestational age at the cancer diagnosis and epithelial histopathology type. That factors have better prognosis than early gestational age and non-epithelial histopathology clinically (p=0.18; CI 95% 0.4-104.2; OR 6,5) and (p=0.29; CI 95% 0.36-30.12; OR 3.28). Timing of surgery intervention improve prognosis of pregnancy statistically and clinically significant (p=0.02; OR=4.2). Conclusion: Factors on pregnancy complicated by ovarian cancer that is late gestational age at the cancer diagnosis, epithelial histopathology type and timing of surgery intervention type II-III improved fetal and maternal prognosis. Best management of pregnancy lead to better prognosis. Keywords: prognosis of pregnancy, ovarian cancer.
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