Gorham-Stout disease with thoracic, vertebral and pleural involvement: case report and literature review

Gorham-Stout disease, pathology with vascular proliferation, angiomatosis and bone lymphangiomatosis that causes progressive osteolysis and loss of bone mass. Thoracic, pulmonary or pleural affection leads to a compromised respiratory function that can lead to a fatal outcome. The mandibular involvement may lead to the development of obstructive sleep apnea. The etiopathogenesis is currently unknown and occurs sporadically. Since the description of the pathology in 1838, there have been documented more than 200 cases in the literature being 50 of these in pediatric population. We report the case of a 13-year-old patient with Gorham-Stout disease with thoracic, vertebral and pleural involvement.