Antineoplastic Therapies related Cardiotoxicity

Antineoplastic therapies related cardiotoxicity has become a significant concern for the long-term survival of cancer patients going through such treatments. Thus knowing the existing types of therapies that causes cardiotoxicity adverse effects as well as exploring their underlying mechanisms is of great clinical importance. In this article, we have made a review on the main types of cardiotoxicity-related antineoplastic therapies, which could be divided into traditional chemotherapy, targeted therapy, radiotherapy and immune therapy; and later we discussed on the possible mechanism of each of them. Besides, the monitoring and inspection methods which consists mainly of the echocardiography, MRI as well as some biomarkers, various as the methods, right now there however doesn’t exist any standard or criterion for the early and timely detection of the cardiotoxicity effects for these patients. Furthermore, next we made a summary on the protection or prevention of the heart for patients treated or going to be treated with antineoplastic therapies, mainly based on the chemotherapy. Lastly, we made a discussion on the problems and challenges we are facing and drew a prospect of the future on cardio-oncology.