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引用次数: 0
摘要
研究了野生型λ sus 9和T4 AM B17噬菌体在35S预标记细菌中生长并在-196度下储存的反向突变。在λ和T4噬菌体中均未观察到35S的致突变作用。这表明，35S的分解对DNA聚合酶的性质没有影响，而DNA聚合酶的致突变活性可能归因于35S的分解。
Effects of disintegration of incorporated 35S on mutation frequency.
The reverse mutation to the wild type of lambda sus 9 and T4 AM B17 bacteriophages, grown in bacteria prelabeled with 35S and stored at--196 degrees, was studied. No mutagenic effect of 35S was observed in both, lambda and T4 bacteriophages. It is suggested that there is no influence of 35S disintegrations on the properties of DNA polymerase to which the mutagenic activity could be attributed.
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