{"title":"深入了解类风湿关节炎、指标(疾病活动评分28 (DAS28)、ESR、CRP、简化疾病活动指数(SDAI)、临床疾病活动指数(CDAI)、患者整体健康)及其与疾病活动水平的相关性","authors":"Syed Faaez Ul Hassan Naqvi, Gul Shehnaz","doi":"10.31703/giidr.2020(v-i).01","DOIUrl":null,"url":null,"abstract":"Rheumatoid arthritis as one of the autoimmune diseases is more prevalent now than ever before. Being more common in women than men, RA has been focused by researchers to invent a therapeutic agent for effective clinical response. Various Diagnostic biomarkers are being used for early diagnosis of RA depending upon their selectivity and specificity. Certain indexes for RA disease activity evaluation are used for assessment of disease on a continuous scale. Disease activity Score combined with laboratory data result and imaging technologies makes the decision of treatment strategies easier than before. Traditionally, TNFi are the most used agents since a decade and first choice of treatment by clinicians, however, combination therapy with DMARD is used in inadequate responders. Despite all the advancements in treatment of RA and proved remission possibility using latest biological agents, studies are needed to ensure quick clinical outcomes and remission probability in larger fraction of people.","PeriodicalId":369025,"journal":{"name":"Global Immunological & Infectious Diseases Review","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Deep Insight on Rheumatoid Arthritis, Indexes (Disease Activity Score 28 (DAS28), ESR, CRP, Simplified Disease Activity Index (SDAI), Clinical Disease Activity Index (CDAI), Patient Global Health) and Correlation with the Level of Disease Activity\",\"authors\":\"Syed Faaez Ul Hassan Naqvi, Gul Shehnaz\",\"doi\":\"10.31703/giidr.2020(v-i).01\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Rheumatoid arthritis as one of the autoimmune diseases is more prevalent now than ever before. Being more common in women than men, RA has been focused by researchers to invent a therapeutic agent for effective clinical response. Various Diagnostic biomarkers are being used for early diagnosis of RA depending upon their selectivity and specificity. Certain indexes for RA disease activity evaluation are used for assessment of disease on a continuous scale. Disease activity Score combined with laboratory data result and imaging technologies makes the decision of treatment strategies easier than before. Traditionally, TNFi are the most used agents since a decade and first choice of treatment by clinicians, however, combination therapy with DMARD is used in inadequate responders. Despite all the advancements in treatment of RA and proved remission possibility using latest biological agents, studies are needed to ensure quick clinical outcomes and remission probability in larger fraction of people.\",\"PeriodicalId\":369025,\"journal\":{\"name\":\"Global Immunological & Infectious Diseases Review\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Global Immunological & Infectious Diseases Review\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31703/giidr.2020(v-i).01\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global Immunological & Infectious Diseases Review","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31703/giidr.2020(v-i).01","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Deep Insight on Rheumatoid Arthritis, Indexes (Disease Activity Score 28 (DAS28), ESR, CRP, Simplified Disease Activity Index (SDAI), Clinical Disease Activity Index (CDAI), Patient Global Health) and Correlation with the Level of Disease Activity
Rheumatoid arthritis as one of the autoimmune diseases is more prevalent now than ever before. Being more common in women than men, RA has been focused by researchers to invent a therapeutic agent for effective clinical response. Various Diagnostic biomarkers are being used for early diagnosis of RA depending upon their selectivity and specificity. Certain indexes for RA disease activity evaluation are used for assessment of disease on a continuous scale. Disease activity Score combined with laboratory data result and imaging technologies makes the decision of treatment strategies easier than before. Traditionally, TNFi are the most used agents since a decade and first choice of treatment by clinicians, however, combination therapy with DMARD is used in inadequate responders. Despite all the advancements in treatment of RA and proved remission possibility using latest biological agents, studies are needed to ensure quick clinical outcomes and remission probability in larger fraction of people.