{"title":"基于硅纳米线电解质/NiOx/SiO2/n-Si传感器的前列腺癌生物标志物检测","authors":"Anisha Roy, J. Qiu, S. Maikap","doi":"10.1109/VLSI-TSA.2018.8403861","DOIUrl":null,"url":null,"abstract":"Sarcosine as a prostate cancer biomarker has been detected by using Si naowire based electrolyte/NiO<inf>x</inf>/SiO<inf>2</inf>/n-Si sensor for the first time. A long nanowire (14 ^m) by chemically etched is observed by scanning electron microscope (SEM) images. A 2 nm-thick NiO<inf>x</inf> membrane on SiO<inf>2</inf>/n-Si structure shows low concentration of 1 pM H<inf>2</inf>O<inf>2</inf> sensing as well as sarcosine of 10 pM has been detected because Ni<sup>2</sup>+ oxidation state changes to Ni<sup>3</sup>+ state.","PeriodicalId":209993,"journal":{"name":"2018 International Symposium on VLSI Technology, Systems and Application (VLSI-TSA)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prostate cancer biomarker detection by using Si nanowire based electrolyte/NiOx/SiO2/n-Si sensors\",\"authors\":\"Anisha Roy, J. Qiu, S. Maikap\",\"doi\":\"10.1109/VLSI-TSA.2018.8403861\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Sarcosine as a prostate cancer biomarker has been detected by using Si naowire based electrolyte/NiO<inf>x</inf>/SiO<inf>2</inf>/n-Si sensor for the first time. A long nanowire (14 ^m) by chemically etched is observed by scanning electron microscope (SEM) images. A 2 nm-thick NiO<inf>x</inf> membrane on SiO<inf>2</inf>/n-Si structure shows low concentration of 1 pM H<inf>2</inf>O<inf>2</inf> sensing as well as sarcosine of 10 pM has been detected because Ni<sup>2</sup>+ oxidation state changes to Ni<sup>3</sup>+ state.\",\"PeriodicalId\":209993,\"journal\":{\"name\":\"2018 International Symposium on VLSI Technology, Systems and Application (VLSI-TSA)\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2018 International Symposium on VLSI Technology, Systems and Application (VLSI-TSA)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/VLSI-TSA.2018.8403861\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2018 International Symposium on VLSI Technology, Systems and Application (VLSI-TSA)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/VLSI-TSA.2018.8403861","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Prostate cancer biomarker detection by using Si nanowire based electrolyte/NiOx/SiO2/n-Si sensors
Sarcosine as a prostate cancer biomarker has been detected by using Si naowire based electrolyte/NiOx/SiO2/n-Si sensor for the first time. A long nanowire (14 ^m) by chemically etched is observed by scanning electron microscope (SEM) images. A 2 nm-thick NiOx membrane on SiO2/n-Si structure shows low concentration of 1 pM H2O2 sensing as well as sarcosine of 10 pM has been detected because Ni2+ oxidation state changes to Ni3+ state.