2015年1月- 2017年12月某大学医院早发性(<40岁)与晚发性(≥40岁)2型糖尿病成人危险因素差异

M. Caro, E. Cunanan
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引用次数: 0

摘要

背景:糖尿病仍将是全球健康的一大威胁。不再仅仅是一种成熟年龄的疾病,现在有一种公认的趋势是向年轻人倾斜。在这一易感但至关重要的人群中,早期诊断可导致早期干预和预防并发症。目的:比较诱发成人早发性糖尿病的危险因素(27.50 kg/m2是导致糖尿病早发性的重要危险因素)。心肌梗死和肾病在晚发组多见,而视网膜病变在早发组多见。最后,只有视网膜病变和神经病变与糖尿病持续时间延长显著相关。结论:菲律宾人的平均年龄比白种人至少年轻5岁。早发组的大多数患者肥胖,代谢谱更差。早发组以视网膜病变多见,而后发组以心肌梗死和神经病变多见。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Difference in Risk Factors Between Adults With Early-Onset (<40 Years Old) Versus Late-Onset (≥40 Years Old) Type 2 Diabetes in a University Hospital From January 2015-December 2017
Background: Diabetes will remain a threat to global health. No longer just a disorder of mature age, there is now a well-recognized trend towards the young. Early diagnosis leads to early intervention and prevention of complications in this susceptible but vital portion of the population. Objective: To compare the risk factors predisposing adults to early-onset (<40 years old) versus late-onset (≥40 years old) type 2 diabetes at the University of Santo Tomas Hospital from January 2015-December 2017. Methods: This is a retrospective review of medical records. All adult patients who fulfilled the inclusion criteria from January 2015 to December 2017 were included in the study. Data from charts were reviewed and analyzed. Results: The early-onset group had a mean age of 34 years, while the late-onset group had a mean age of 51 years. The early-onset diabetics were mostly obese, had higher HbA1c, worse lipid profiles, and had a positive family history of diabetes. Only a BMI of >27.50 kg/m2 was found to be a significant risk factor contributing to early-onset of diabetes. Myocardial infarction and nephropathy were more frequent in the late-onset group while retinopathy was more common in the early-onset group. Lastly, only retinopathy and neuropathy were significantly associated with longer duration of diabetes. Conclusion: The mean age of Filipinos was at least 5 years younger than the studies done on Caucasians. Most patients in the early-onset group were obese and had worse metabolic profiles. Retinopathy was more common in the early-onset group, while myocardial infarction and neuropathy were more common in the latter.
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