用于连续监测应用的柔性无酶葡萄糖微传感器

TRANSDUCERS 2009 - 2009 International Solid-State Sensors, Actuators and Microsystems Conference Pub Date : 2009-06-21 DOI:10.1109/SENSOR.2009.5285725

Y.J. Lee, J. Kim, J. Park

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引用次数: 10

摘要

在生物相容性PET(聚对苯二甲酸乙二醇酯)薄膜上设计、制造了纳米多孔Pt(铂)工作电极的柔性无酶葡萄糖微传感器，并对其进行了表征。制备的柔性传感器的电极表面粗糙度系数(RF)为106.5，远高于溅射金电极的传感器。该传感器在5 ~ 30 mM的葡萄糖浓度范围内具有20.16µA/mM·cm2的高灵敏度，相关系数为0.958，且不影响推断物种，检出限低至25µM，具有高度稳定的回收率。该传感器的灵活性、生物相容性和无酶特性为连续血糖监测应用提供了强大的优势。

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Flexible enzyme free glucose micro-sensor for continuous monitoring applications

Flexible enzyme free glucose micro-sensor with nanoporous Pt (Platinum) working electrode on a bio-compatible PET (Polyethylene Terephthalate) film was designed, fabricated, and characterized for continuous monitoring applications. The fabricated flexible sensor showed electrode surface RF (roughness factor) of 106.5 which was much higher than that of the sensor with sputtered Au electrode. The fabricated sensor exhibited high sensitivity of 20.16 µA/mM·cm2 with correlation coefficient of 0.958 without affecting inferring species in glucose concentrations ranged from 5 to 30 mM. It also exhibited low detection limit of 25 µM, and highly stable recovery characteristic. Flexibility, bio-compatibility, and enzyme free characteristic of the fabricated sensor are strong advantages for continuous glucose monitoring applications.

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TRANSDUCERS 2009 - 2009 International Solid-State Sensors, Actuators and Microsystems Conference

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