门诊药剂师诊所免疫相关不良事件的倡议

K. Hamatake, Kazuaki Kojima
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引用次数: 1

摘要

早期发现是控制副作用的关键,因为免疫相关不良事件(irAEs)正变得越来越严重,而且它们的发病时间不同。在我院,我们开展了门诊药师门诊,通过自我保健实践,早期发现免疫检查点抑制剂的病例。通过对207例病例的回顾性调查发现,门诊药师诊所药师建议发现的irAEs的比例随着时间的推移而增加,即使对发病时间较晚的irAEs也有较高的检出率。严重irae发生率高于直接上市后监测,且考虑了不同因素。门诊药师门诊虽然存在一些问题,但取得了一定的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Initiatives for immune-related adverse events by the outpatient pharmacist clinic
Early detection is the key in managing side effects because immune-related adverse events (irAEs) are becoming more serious, and their onset time differs. In our hospital, we conducted an outpatient pharmacist clinic for early detection of irAEs by self-care practice for the cases of immune checkpoint inhibitor administration. As a result of a retrospective survey of 207 cases, the percentage of irAEs found by pharmacist’s suggestion of the outpatient pharmacist clinic increased over time, and a high detection ratio was obtained even for irAEs with a late onset time. The incidence of serious irAEs was higher than that in the immediate post-marketing surveillance, and different factors were considered. Although there were some problems, the outpatient pharmacist clinic had a certain effect.
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