微流控装置制造用滚轮压印装置的设计与制造

A. Vijayaraghavan, Stephen Jayanathan, M. Helu, D. Dornfeld
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引用次数: 2

摘要

微流控装置在从分子生物学到生物防御的各种应用中越来越受欢迎。然而,这种技术的广泛采用受到缺乏高效和具有成本效益的制造工艺的限制。本文重点介绍了用于快速、低成本制造微流体器件的滚轮压印工艺。在这个过程中,一个表面有凸起特征的圆柱辊通过在固定的工件基材上滚动并机械地使其变形来产生压痕。滚筒压印旨在取代为实验室规模原型开发的过程,这些过程往往不可扩展,并且具有高设备要求和开销。讨论了PDMS软光刻技术在微流控器件大规模制造中的局限性。我们还讨论了一个简单的滚筒压印装置的设计、制造和测试。该压印机是根据精密机械设计原理开发的,并使用三轴机床进行驱动和位置测量。提出了精密压印辊微加工的框架。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
DESIGN AND FABRICATION OF A ROLLER IMPRINTING DEVICE FOR MICROFLUIDIC DEVICE MANUFACTURING
Microfluidic devices are gaining popularity in a variety of applications, ranging from molecular biology to bio-defense. However, the widespread adoption of this technology is constrained by the lack of efficient and cost-effective manufacturing processes. This paper focuses on the roller imprinting process, which is being developed to rapidly and inexpensively fabricate micro-fluidic devices. In this process, a cylindrical roll with raised features on its surface creates imprints by rolling over a fixed workpiece substrate and mechanically deforming it. Roller imprinting aims to replace processes that were developed for laboratory scale prototyping which tend to not be scalable and have high equipment requirements and overheads. We discuss the limitations of PDMS soft lithography in large-scale manufacture of microfluidic devices. We also discuss the design, fabrication, and testing of a simple roller imprinting device. This imprinter has been developed based on the principles of precision machine design and is implemented using a three-axis machine tool for actuation and position measurement. A framework for the micromachining of precision imprint rolls is also presented.
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