{"title":"人胎盘的体外灌注研究。人胎盘中葡萄糖转运系统的一些特点。","authors":"P A Rice, J E Rourke, E L Nesbitt","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In vitro perfusion studies of glucose transport in the human placenta show saturation kinetics at high glucose concentrations and competitive inhibition of glucose transfer by the nonmetablizable glucose analog 3-O-methyl-alpha-D glucopyranoside. These characteristics provide further evidence that glucose is transported by a facilitated diffusion process in the human placenta.</p>","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"7 4","pages":"213-21"},"PeriodicalIF":0.0000,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"In vitro perfusion studies of the human placenta. IV. Some characteristics of the glucose transport system in the human placenta.\",\"authors\":\"P A Rice, J E Rourke, E L Nesbitt\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In vitro perfusion studies of glucose transport in the human placenta show saturation kinetics at high glucose concentrations and competitive inhibition of glucose transfer by the nonmetablizable glucose analog 3-O-methyl-alpha-D glucopyranoside. These characteristics provide further evidence that glucose is transported by a facilitated diffusion process in the human placenta.</p>\",\"PeriodicalId\":75889,\"journal\":{\"name\":\"Gynecologic investigation\",\"volume\":\"7 4\",\"pages\":\"213-21\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1976-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gynecologic investigation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gynecologic investigation","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
人胎盘中葡萄糖转运的体外灌注研究显示,高葡萄糖浓度下的饱和动力学和不可代谢的葡萄糖类似物3- o -甲基- α - d葡萄糖吡喃苷对葡萄糖转运的竞争性抑制。这些特征提供了进一步的证据,证明葡萄糖是通过一个易于扩散的过程在人胎盘中运输的。
In vitro perfusion studies of the human placenta. IV. Some characteristics of the glucose transport system in the human placenta.
In vitro perfusion studies of glucose transport in the human placenta show saturation kinetics at high glucose concentrations and competitive inhibition of glucose transfer by the nonmetablizable glucose analog 3-O-methyl-alpha-D glucopyranoside. These characteristics provide further evidence that glucose is transported by a facilitated diffusion process in the human placenta.