卵母细胞的低温保存

G. Allahbadia, G. Gandhi, Priyanka Desai
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引用次数: 0

摘要

长期以来,配子和胚胎的低温保存一直是临床医生和科学家取得成功的主要障碍。然而,近年来低温生物学领域的技术进步为冷冻不同发育阶段的配子和胚胎提供了多种选择。体外受精世界转向自然周期体外受精和选择性单胚胎移植的趋势使冷冻技术成为研究的前沿。尽管如此,寒冷诱导的人类配子和胚胎变化的复杂性可能会影响细胞内和发育过程,需要了解。转录组学、蛋白质组学和代谢组学平台有望在低温保存过程中阐明这些复杂的过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cryopreservation of Oocytes
For a long time, the cryopreservation of gametes and embryos remained a major hurdle for the clinicians and scientists in terms of success. However, recent technical advancement in the field of cryobiology has opened up various options for freezing gametes and embryos at different developmental stages. The tendency of the IVF world to switch over to naturalcycle IVF and to elective single-embryo transfer has put cryotechnology in the forefront of research. Still, the intricacies of the cold-induced changes in human gametes and embryos that could affect the intracellular and developmental processes need to be known. The transcriptomics, proteomics and metabolomic platforms hold promise for elucidating these complex processes during cryopreservation processes.
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