[HL-A型输血。一项有2380名捐赠者参与的研究[作者简介]。

C Bouillenne, P Leclercq, J Brocteur, A André
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引用次数: 0

摘要

接受反复输血的患者迟早会产生抗hl - a免疫。从长远来看,通过输入“去血细胞”的血液来预防或延缓这种免疫似乎是一个模糊的希望。因此,使用来自HL-A系统的献血者的血液变得至关重要。在这项研究中,我们研究了如果为110名受体提供2380名HL-A型供体会发生什么。25%的受者可以从5个以上与自己具有相同HL-A型的献血者处获得血液,其中71%的人可以从5个以上的献血者处获得血液,每个位点至少共享一种抗原(并且已知它们之间没有不同的抗原)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Transfusion of blood with HL-A type. A study with 2,380 donors (author's transl)].

Patients receiving repeated transfusions sooner or later develop an anti-HL-A immunization. To prevent or to delay this immunization by transfusing "deleucocyted" blood appears in the long run, to be a vague hope. So, it became essential to use blood from donors typed for the HL-A system. In this study we have examined what would happen if a pool of 2,380 HL-A type donors were available for 110 recipients. Twenty five per cent of the recipients will have blood available from more than 5 donors with the same HL-A types as themselves, and 71% of them can receive blood from more than 5 donors sharing at least one antigen at each locus (and with no antigen known to be different between them).

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