0.25%罗哌卡因加曲马多与0.25%布比卡因加曲马多在腹部和下肢手术术后硬膜外镇痛的比较研究

Shilpashri Am
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引用次数: 1

摘要

背景:急性术后疼痛的治疗是现代卫生服务的重要内容。近年来,硬膜外镇痛有较好的应用前景。局部麻醉剂如布比卡因和罗哌卡因给予硬膜外空间有助于成功的术后疼痛管理。局部麻醉剂中加入阿片类药物具有协同镇痛作用。目的:比较布比卡因与罗哌卡因联合曲马多用于术后硬膜外镇痛的镇痛效果,包括镇痛质量、作用时间及不良反应。材料与方法:选取年龄18 ~ 60岁、美国麻醉医师学会I级和II级、择期行腹部和下肢手术的患者50例,随机分为两组。BT组给予0.25%布比卡因+曲马多(1 mg/kg), RT组给予0.25%罗哌卡因+曲马多(1 mg/kg)。监测患者镇痛的发作、持续时间和质量、心肺稳定性以及任何副作用或运动阻滞。结果:两组患者平均镇痛起效时间和镇痛质量相当。RT组作用时间(417.20±42.52 min)明显长于BT组(356.00±49.03 min), p < 0.001。与rt组相比,BT组血压显著下降。BT组有4例患者出现运动阻断,而rt组无一例。两组均无明显副作用。研究文章
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Postoperative Epidural Analgesia between 0.25% Ropivacaine Plus Tramadol and 0.25% Bupivacaine Plus Tramadol in Abdominal and Lower Limb Surgeries - A Comparative Study
Background: The treatment of acute postoperative pain is important for modern health services. Analgesia through epidural route appears to have a brighter prospect these days. Local anesthetics like bupivacaine and ropivacaine given in epidural space have helped in successful postoperative pain management. Addition of opioids to local anesthetics has a synergistic action on analgesia. Objective: To compare analgesic efficacy of Bupivacaine and Ropivacaine in combination with Tramadol for postoperative epidural analgesia in terms of the quality of analgesia, its duration of action and side effects involved. Materials and methods: 50 patients of age 18-60 years with American Society of Anesthesiologists grade I & II, undergoing elective abdominal and lower limb surgeries were randomly allotted to each of the 2 groups. Group BT received 0.25% bupivacaine + tramadol (1 mg/kg) and group RT received 0.25% ropivacaine + tramadol (1 mg/kg) epidurally. Patients were monitored for onset, duration and quality of analgesia, cardiorespiratory stability and for any side effects or motor blockade. Results: The mean time of onset of analgesia and quality of analgesia were comparable between the two groups. The duration of action in group RT (417.20 ± 42.52 mins) was found significantly prolonged than group BT (356.00 ± 49.03 mins) with p < 0.001. Significant fall in blood pressures was seen in group BT when compared with group RT. 4 patients in group BT had motor blockade while none in group RT. There were no significant side effects in both the groups. Research Article
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